Editing Radiology 272 2 . Pp

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Eighteen subjects had end-tidal partial pressure of carbon dioxide (PetCO2) elevated by 10 mm Hg, and myocardial perfusion was monitored with myocardial blood oxygen stage-dependent (Bold) magnetic resonance (MR) imaging. Animal studies were accepted by the institutional animal care and use committee. 7) induced stenosis of the left anterior descending artery (LAD) underwent vasodilator challenges with hypercapnia and adenosine. LAD coronary blood movement velocity and free-breathing myocardial Bold MR responses were measured at every intervention. Appropriate statistical checks have been performed to guage measured quantitative changes in all parameters of interest in response to changes in partial strain of carbon dioxide. 75). In intact canines, there was a sigmoidal relationship between Bold MR response and PetCO2 with a lot of the response occurring over a ten mm Hg span. 99) responses have been similar to that of adenosine infusion. 12). 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